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URB-597 ([3-(3-carbamoylphenyl)phenyl] N-cyclohexylcarbamate), also known as KDS-4103, is an inhibitor of endocannabinoids metabolism and a selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH).

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URB-597 ([3-(3-carbamoylphenyl)phenyl] N-cyclohexylcarbamate), also known as KDS-4103, is an inhibitor of endocannabinoids metabolism and a selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH), the main enzyme responsible for the degradation of the cannabinoid neurotransmitter anandamide (N-arachidonoylethanolamine or AEA). Such an inhibition is responsible for the accumulation of AEA in the central and peripheral nervous systems where it can continue to activate receptors. Studies in mice have shown that a notable reduction in FAAH activity resulted in reduced sensation of pain.

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